DNA/RNA Shield™
  • Nucleic acid preservation (at ambient temperature; cold-free).
  • Pathogen inactivation (bacteria, fungus, parasites & viruses).
  • Streamlined purification (no reagent removal, universally compatible, automatable).

DNA and RNA in stool is effectively stabilized in DNA/RNA  Shieldat ambient temperature. Graphs show: spike-in DNA  and RNA controls from stool purified at the indicated time  points and analyzed by (RT)qPCR.

Viruses, bacteria and yeast are effectively inactivated by DNA/RNA Shield. Samples  containing the infectious agent (virus, bacteria, yeast) were treated for 5 minutes with  DNA/RNA Shield™ or mock (PBS). Titer (PFU) was subsequently determined by plaque  assay. Validated by: Influenza A – D. Poole and Prof. A. Mehle, Department of Medical  Microbiology and Immunology, University of Wisconsin, Madison; Ebola (Kikwit) – L.  Avena and Dr. A. Griffiths, Department of Virology and Immunology, Texas Biomedical  Research Institute; HSV-1/2 – H. Oh, F. Diaz and Prof. D. Knipe, Virology Program, Harvard  Medical School; E. coli, L. fermentum, B. subtilis, S. cerevisiae – Zymo Research).

*Disclaimer: This graph only displays results from E. coli inactivation. Each microbe was tested independently  and were combined into one graph for brevity. Bacterial cultures were grown between 108 – 109 cells and yest  cultures were grown between 107 – 108 cells.

No Reagent Removal. Simple, direct purification using Zymo Research Purification Products*.

Sample in DNA/RNA Shield

Simply add binding reagent

Bind directly

to spin-column or Magbeads

Eluted DNA/RNA

is ready to use

Product Cat. No. Size
DNA/RNA Shield™ R1100-50 50ml R1100-8-S (8 ml)
DNA/RNA Shield™ (2X Concentrate) R1200-25 25ml -
DNA/RNA Shield™ Collection Devices
Blood Collection Tube

Evacuated blood tube (16 x 100 mm) filled with 6 ml of DNA/RNA Shield™

for the direct collection of 3 ml whole-blood (human or animal).

Fecal Collection Tube

15 ml container (prefilled with 9 ml DNA/RNA Shield™) for the direct  collection of up to 1 gram and/or 1 ml stool. Collection spoon is included  in the container screwcap.

Microbe & Tissue Lysis Tubes

2 ml collection tube (prefilled with 1 ml DNA/RNA Shield™) and  BashingBeads™ for the collection and homogenization of microbial or  tissue samples.

Swab and Collection Tube

5 ml screwcap container (12 x 80 mm) filled with 1 ml DNA/RNA Shield™

and a sterile swab for specimen collection.

Product Cat. No. Size
DNA/RNA Shield™ - Blood Collection Tube R1150 50 pack -
DNA/RNA Shield™ - Fecal Collection Tube R1101 10 pack -
NA/RNA Shield™ Lysis Tube (Microbe) R1103 50 pack -
DNA/RNA Shield™ Lysis Tube w/ Swab (Microbe) R1104 50 pack -
DNA/RNA Shield™ Lysis Tube (Tissue) R1105 50 pack -
DNA/RNA Shield™ - Swab & Collection Tube R1106
R1107
10pack (1 ml fill)
50 pack (1 ml fill)
R1106S (10 pack)