Welcome to Pacific Informatics!
We are pioneers in the field of bioinformatics, offering an exceptional single-cell RNA sequencing (scRNA-seq) service that is unrivaled in its sophistication and precision.
BASIC Upstream Chromium scRNA-seq Analysis – Our foundational service offers:
- Sequencing Quality Control – Ensuring validity and reliability of the data collected.
- CellRanger Quality Control – Additional quality checks for the highest fidelity of your alignment and count data.
ADVANCED Downstream Chromium scRNA-seq Analysis – Our advanced suite includes:
- Cell Type Annotation – Precise identification and categorization of cell types.
- Trajectory Inference – Pseudotime analysis for tracking cell development and progression.
- Differential Gene Expression Analysis – Utilizing pseudo-bulk and Gene Ontology analysis to pinpoint key gene expression variances among groups.
- Cell-Cell Communication Analysis – Detailed insights into cell interactions and relationships.
Smart-seq3 Analysis (Coming Soon) – We’re preparing to offer services powered by Smart-seq3, an advanced technology that provides unparalleled full-length transcript coverage and superior sensitivity for gene and transcript detection:
- Upstream Smart-seq3 scRNA-seq Analysis (BASIC) – Includes sequencing quality control. Examples of quality control reports will be provided.
- Downstream Smart-seq3 scRNA-seq Analysis (ADVANCE) – Features cell type annotation, differential gene expression analysis for pseudo-bulk and gene ontology, isoform expression analysis, and allelic specific expression analysis.
Spatial Transcriptomics with Visium (Coming Soon) – We’re developing innovative new services utilizing 10X Genomics’ Visium, a cutting-edge technology offering high-resolution insights into gene expression within their spatial context:
- Upstream Visium scRNA-seq Analysis (BASIC) – Involves sequencing quality control and SpaceRanger quality control.
- Downstream Visium scRNA-seq Analysis (ADVANCE) – service details coming soon.
- Regional Annotation – High-resolution analysis of gene expression within specific tissue regions.
- Spatial Deconvolution – Breakdown of complex gene expression data into meaningful, spatially resolved components.
- Regional Function Analysis – Insightful examination of gene function within specific spatial regions.
- Spatial Co-localization and Cell-cell Interaction Analysis – Identification of cellular communication networks and determination of cell-cell interaction mediating genes.
- Differential Gene Expression Analysis for Regions and Gene Ontology Analysis – Identifying differentially expressed region-specific genes and categorization of these genes into functional groups.
Results Delivery – Efficient and timely distribution of results to our esteemed clients. At Pacific Informatics, we prioritize your success.
With Pacific Informatics, you are not just receiving a service, but a partnership dedicated to helping you achieve your research and business objectives.